Post-extraction socket, healing or regeneration? Therapeutics and use of PRGF-ENDORET®

In this book, we present a biological approach to the treatment of the post-extraction or post-explantation socket, based on the use of platelet-derived growth factors, aimed at achieving complete regeneration of the post-extraction bed in a simple and predictable manner.

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Description

Following tooth extraction, a series of unavoidable events occurs in the crestal bone of the socket, ultimately leading to healing with a greater or lesser degree of bone resorption. Various biomaterial-based procedures have therefore been developed to prevent socket collapse and promote complete socket regeneration.

In this book, we present a biological approach to the management of the post-extraction socket, based on the use of platelet-derived growth factors to achieve complete regeneration of the post-extraction or post-explantation site in a simple and predictable manner. We also address immediate implants from an innovative perspective, according to the specific characteristics of the socket and the implant to be used, developing treatment algorithms for each of the clinical situations that may be encountered. All of this is illustrated with clinical cases and explanatory videos that make the experience more enriching.

TitlePost-extraction socket, healing or regeneration? Therapeutics and use of PRGF-ENDORET®
Author
Year of edition2026
Edition1
Number of pages236

Eduardo Anitua Aldecoa

Doctor of medicine and surgery

 

Biography

 

Degree in Medicine and Surgery from the University of Salamanca.

Doctor of Medicine from the University of Valencia.

Specialised in Stomatology from the University of the Basque Country (UPV/EHU).

Diploma in Prostheses and Occlusion from the Pankey Institute (Florida, USA).

Visiting Professor at over 20 universities in the USA (Harvard, Boston, Tufts, Pennsylvania, New Orleans), Germany (Berlin), England (Bristol), Italy (Milan, Turin), India, Mexico, Brazil, Portugal, Argentina, Colombia, Venezuela, Uruguay, Spain (Seville, Madrid, Barcelona, Murcia, Oviedo, etc.).

 

Personal website: www.eduardoanitua.com

1. BIOLOGICAL BASIS OF POST-EXTRACTION SOCKET REGENERATION
▪ Molecular and cellular foundations of tissue healing
▪ Anatomy and physiology of the gingiva and alveolar bone
▪ Alveolar processes. Gingival tissue and alveolar bone
▪ Post-extraction socket regeneration

2. DENTAL EXTRACTION
Preliminary protocol and patient assessment
▪ Indications and contraindications for dental exodontia

3. DENTAL EXTRACTION AND ITS PROCEDURE
▪ Dental extraction
▪ Dental extraction: teeth with an indication for extraction
▪ The dental extraction process
▪ Complex extractions
▪ Complications of dental extraction

4. PLASMA RICH IN GROWTH FACTORS: PRGF – ENDORET®
Sequence and protocol of use in dental extraction
▪ Platelets and tissue regeneration
▪ PRGF – ENDORET®: concepts
▪ PRGF – ENDORET®: preparation method
▪ PRGF – ENDORET® formulations
▪ Protocol for the use of PRGF – ENDORET® in the post-extraction socket
▪ Use of PRGF – ENDORET® in the post-extraction socket.

5. APPLICATIONS OF PRGF – ENDORET® IN DENTISTRY
▪ PRGF – ENDORET® in the post-extraction socket
▪ Other applications of PRGF – ENDORET® in the oral field

6. BISPHOSPHONATES, ANTIRESORPTIVE DRUGS AND DENTAL EXODONTIA
Use of PRGF – ENDORET® in this field
▪ Introduction
▪ Prevention of ONJ
▪ PRGF – ENDORET® in the adjunctive treatment of ONJ

7. IMMEDIATE POST-EXTRACTION AND POST-EXPLANT IMPLANT AND USE OF PRGF – ENDORET®
Reversibility of implant treatments
▪ The immediate post-extraction implant
▪ Dimensional changes in the post-extraction socket
▪ Importance of implant surface in bone growth within the gap
▪ PRGF – ENDORET® as a regenerative material and filling material
▪ Immediate post-explant implant

8. IMMEDIATE VS EARLY IMPLANT
Reflection on its indication based on experience
▪ The early insertion implant
▪ Early implant insertion: step-by-step technique
▪ Early implant insertion: treatment predictability

9. DENTAL AUTOTRANSPLANTATION
An alternative to the implant
▪ Dental autotransplantation. History and evolution
▪ Autotransplantation protocol
▪ Implant or autotransplant?

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